NIH is pleased to present the 2014-2015 Alzheimer’s Disease Progress Report: Advancing Research Toward a Cure. This annual report details NIH-supported and -conducted Alzheimer’s disease research initiatives, objectives, and advances during calendar year 2014 and early 2015. New findings and investments described in this report are organized in categories determined by the Common Alzheimer Disease Research Ontology (CADRO) of the International Alzheimer’s Disease Research Portfolio (IADRP).
The NIH-supported IADRP database, developed in collaboration with the Alzheimer’s Association, captures a wide spectrum of current Alzheimer’s disease and related dementias research investments and resources in the United States and internationally. The CADRO categories, which have informed the goals and objectives set forth in the National Plan to Address Alzheimer’s Disease, have proven useful in tracking spending in specific areas of research, making the categories an ideal structure for reporting on scientific advances.
Through NIH’s research efforts on Alzheimer’s and related dementias, it is evident that we have reached a new and increasingly collaborative era of research, characterized by open national discussion of research goals and priorities and sharing of research data aimed at accelerating discovery. We dedicate this report to people with Alzheimer’s disease and their families, and to the thousands of research volunteers who give their time and more to help find a cure. Working together, we look toward a future where memories and lives are no longer lost to this devastating disease.
This year, the report includes much of the scientific content found in the first-ever NIH Bypass Budget Proposal for Fiscal Year 2017. That report estimates the additional funding needed to reach the ultimate research goal of the National Plan—to effectively treat and prevent Alzheimer’s and related dementias by 2025. The proposal is submitted annually by NIH to the President, who reviews and transmits the estimate to the Congress.
Many Institutes and Centers contribute to the NIH research effort to better understand Alzheimer’s and related dementias: the National Institute on Aging (NIA), the lead institute on Alzheimer’s research at NIH; National Institute of Neurological Disorders and Stroke; National Institute of Mental Health; National Institute of Nursing Research; National Institute of Biomedical Imaging and Bioengineering; National Institute of Child Health and Human Development; National Institute of Environmental Health Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Dental and Craniofacial Research; National Heart, Lung, and Blood Institute; Fogarty International Center; and National Center for Advancing Translational Sciences.